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Rab 3 GAP p130 Polyclonal Antibody, 50ul Bio-Reaction Tube Three alternatively spliced transcript variants

SKU: 84648534649

4.1
PLN185.00 PLN235.00

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Rab 3 GAP p130 Polyclonal Antibody, 50ul Bio-Reaction Tube Three alternatively spliced transcript variantsRAB3GAP1 encodes the catalytic subunit of a Rab GTPase activating protein. RAB3 GTPase activating protein catalytic subunit 1 forms a heterodimer with a non catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. RAB3 GTPase activating protein catalytic subunit 1 mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in RAB3GAP1 are associated with Warburg micro syndrome.

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Description

Three alternatively spliced transcript variants that encode different protein isoforms have been described for RBBP5

Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates

The TRAF3-interacting JNK-activating modulator may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit

This gene encodes a protein containing zinc finger domains

Rab 3 GAP p130 Polyclonal Antibody, 50ul Bio-Reaction Tube Three alternatively spliced transcript variantsRAB3GAP1 encodes the catalytic subunit of a Rab GTPase activating protein. RAB3 GTPase activating protein catalytic subunit 1 forms a heterodimer with a non catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. RAB3 GTPase activating protein catalytic subunit 1 mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in RAB3GAP1 are associated with Warburg micro syndrome.

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