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They work by mimicking ghrelin or binding to growth hormone secretagogue receptors (GHS-R), increasing GH and often IGF-1 levels

Human islets culture and treatment Freshly isolated human islets were obtained from the Integrated Islet Distribution Program (IIDP) at City of Hope that was funded by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK, 1UC4DK098085)