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How much medication enters breast milk depends on several factors, including: the type of medicine the dose How often the medicine is taken the age and health of the infant whether the baby was born prematurely Newborn and premature infants may be more sensitive to medications because their liver and kidneys are not fully developed

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Another macroscopic feature commonly observed in AD is the loss of neuromelanin pigmentation in the locus coeruleus with age and is proposed to be toxic and inflammatory when released into the extracellular environment (Serrano-Pozo et al., 2011)