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The Phase 2 Trial Data In the key Phase 2 randomized controlled trial published in the New England Journal of Medicine in 2023 (N=338), participants receiving retatrutide 12 mg weekly lost a mean of 24.2% of body weight at 48 weeks versus 2.1% on placebo [1]

Published: Sep 11, 2025 Written by Klarity Editorial Team Published: Sep 11, 2025 Managing weight loss medications like Tirzepatide and Semaglutide requires careful attention to dosing

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A study published in JAMA Network Open in 2023 found that people who took semaglutide medication lost an average of 5.1% of their body weight