DCMC Rabbit Polyclonal Antibody, 100ul Apoptosis & Autophagy Two transcript variants encoding different

Two transcript variants encoding different isoforms have been found for CSNK2B

May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF

SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participates in Wnt signaling

The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product

DCMC Rabbit Polyclonal Antibody, 100ul Apoptosis & Autophagy Two transcript variants encoding differentThe product of this gene catalyzes the breakdown of malonyl CoA to acetyl CoA and carbon dioxide. Malonyl CoA is an intermediate in fatty acid biosynthesis and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria peroxisomes and the cytoplasm. Mutations in this gene result in malonyl CoA decarboyxlase deficiency.