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3.2 Peripheral GLP-1 signalling in taste pathways: cellular plausibility and translational limits Preclinical studies indicate that GLP-1 is produced in distinct subpopulations of mammalian taste bud cells (TBCs) (13), including TAS1R3-positive and gustducin-positive type II cells, as well as a subset of serotonin-containing type III cells (38)

7.4 Clinical interpretation of divergent response phenotypes From a clinical perspective, patient-reported eating-experience changes during GLP-1RA therapy should be interpreted in relation to the dominant response phenotype rather than assumed to reflect a uniform treatment effect

Which parts of personal medical history shape GLP-1 suitability beyond drug interactions

For twice-daily protocols, aim for a 10-12 hour separation (e.g., 8 AM and 8 PM)