REN3A Rabbit Polyclonal Antibody, 50ul Cell Screening and Imaging and mutations in this gene

and mutations in this gene are a cause of hereditary leukonychia

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also present in lipid rafts

Belongs to the small heat shock protein (HSP20) family

REN3A Rabbit Polyclonal Antibody, 50ul Cell Screening and Imaging and mutations in this geneThis gene encodes a protein that is part of a post splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense mediated mRNA decay (NMD). When translation ends upstream from the last exon exon junction this triggers NMD to degrade mRNAs containing