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Methods Data were from individuals with coronary artery disease who completed the eight items of the emotional domain of the MOS-SS two weeks after receiving cardiac catheterization in Alberta, Canada

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These data suggest that DPP4 directly impairs endothelium-dependent relaxation through a mechanism that involves cyclooxygenase activation, and likely the release of a vasoconstrictor prostanoid

Typically, a more significant decrease in appetite is seen between weeks four and eight, especially as the dose reaches the optimal maintenance level