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Dual-Agonist Mechanism Classification: Tirzepatide is a synthetic peptide drug that operates as a novel dual agonist for the GIP receptor (GIPR) and the GLP-1 receptor (GLP-1R)

Target blood glucose levels are stricter than in non-pregnant individuals: Fasting: 5.3 mmol/L or below One hour after meals: 7.8 mmol/L or below Before meals (if on insulin): 4.05.9 mmol/L These tighter targets help minimise the risk of macrosomia (large baby), polyhydramnios (excess amniotic fluid), and neonatal complications

Why it did so well: Rybelsus stands out as one of Novo Nordisks major current launches, generating sales of approximately $1.65 billion in 2022

Men experiencing new or worsening ED should undergo cardiovascular risk assessment, particularly if they have diabetes, hypertension, high cholesterol, or smoking history