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Cell Cycle 2010

The GHSR pathway is known to mediate multiple ghrelin-related effects beyond GH release 4

d , PCA plot of whole cell, ER-IP and control-IP proteomic data from HEK293T cells expressing control-tag or ER-tag

In contrast, another study demonstrated that transgenic mice with a beta-cell specific deletion of the GLP-1R have impaired intraperitoneal (ip) glucose tolerance but maintain normal oral glucose tolerance (Smith et al., 2014)