IKK Gamma Polyclonal Antibody, 100ul[BT-AP04426] Liquid Handling ＆Storage induction:By p53/TP53

induction:By p53/TP53

leading to histone H3 deacetylation followed by dimethylation of H3 at Lys-9 (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus

Studies of similar proteins in mouse and rat have indicated a potential role in cellular differentiation

Cadherins play a role in development

IKK Gamma Polyclonal Antibody, 100ul[BT-AP04426] Liquid Handling ＆Storage induction:By p53/TP53IKBKG encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.