SFRP1 Polyclonal Antibody, 20ul Protein Expression Dol-P-Man is synthesized from GDP-mannose

Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase

sequence Translated as Gly

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SFRP1 Polyclonal Antibody, 20ul Protein Expression Dol-P-Man is synthesized from GDP-mannoseThis gene encodes a member of the SFRP family that contains a cysteine rich domain homologous to the putative Wnt binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.