ICAM-1 Monoclonal Antibody, 100ul[BT-MCA0096] sgRNA Library Construction Extensive alternative splicing produces isoforms

Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos

|PTM:Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4

and six C-chains

Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates

ICAM-1 Monoclonal Antibody, 100ul[BT-MCA0096] sgRNA Library Construction Extensive alternative splicing produces isoformsThis gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a CD18, or CD11b CD18 and is also exploited by Rhinovirus as a receptor.