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NUCL Polyclonal Antibody, 50ul DNA Libraries Synthesis Most MMPs are secreted as

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NUCL Polyclonal Antibody, 50ul DNA Libraries Synthesis Most MMPs are secreted asNucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.

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Description

Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases

and in this way plays a role in innate immune response

The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family| and to the Ca(2+)/calmodulin-dependent protein kinase subfamily

The encoded protein is a cell surface glycoprotein that is known to complex with integrins

NUCL Polyclonal Antibody, 50ul DNA Libraries Synthesis Most MMPs are secreted asNucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.

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