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TH Polyclonal Antibody, 100ul[BT-AP08988] Nucleic Acid Amplification The protein lacks critical active

SKU: 1264904048

4.1
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TH Polyclonal Antibody, 100ul[BT-AP08988] Nucleic Acid Amplification The protein lacks critical activeTyrosine 3 monooxygenase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have be associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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Description

The protein lacks critical active site residues and thus is suggested to be proteolytically inactive

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Two transcript variants encoding different isoforms have been found for BCR

This gene has a pseudogene on chromosome Y

TH Polyclonal Antibody, 100ul[BT-AP08988] Nucleic Acid Amplification The protein lacks critical activeTyrosine 3 monooxygenase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have be associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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