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iii- toxin based suicide gene therapy: a DNA construct, encoding for a toxic polypeptide whose expression is regulated by a specific transcription regulation element, is delivered to a heterogeneous cell population [179]

The most common side effects for GLP-1 RAs were nausea, vomiting, diarrhea and constipation

Contrarily, a more recent study reported that there was no difference in MDA concentrations in erythrocytes and blood plasma between healthy subjects and OA patients [101]

Chromatin immunoprecipitation (ChIP)- qPCR analysis confirmed that HIF-1 directly binds to the PD-L1 proximal promoter region, enhancing its transcription (158)