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HIF-1 beta Polyclonal Antibody, 100ul[BT-AP09891] Metabolic enzymes CLIC6 (chloride intracellular channel 6)

SKU: 13559095002

4.1
USD108.00 USD143.00

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HIF-1 beta Polyclonal Antibody, 100ul[BT-AP09891] Metabolic enzymes CLIC6 (chloride intracellular channel 6)This gene encodes a protein containing a basic helix loop helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co factor for transcriptional regulation by hypoxia inducible factor 1. Chromosomal translocation

Store: matisco.be · Domain: matisco.be

Description

CLIC6 (chloride intracellular channel 6) encodes a member of the chloride intracellular channel family of proteins

Activity of this protein may inhibit the growth of cancers| particularly pancreatic cancer

thus passing the substrate from one enzyme to another

The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus

HIF-1 beta Polyclonal Antibody, 100ul[BT-AP09891] Metabolic enzymes CLIC6 (chloride intracellular channel 6)This gene encodes a protein containing a basic helix loop helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co factor for transcriptional regulation by hypoxia inducible factor 1. Chromosomal translocation

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