JAK2(Phospho Tyr221) Polyclonal Antibody, 50ul Live Cell Imaging Several alternatively spliced transcript variants

Several alternatively spliced transcript variants have been found

The deduced amino acid sequence exhibits 33% similarity with CD38

also known as STAT-induced STAT inhibitor (SSI)

The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state

JAK2(Phospho Tyr221) Polyclonal Antibody, 50ul Live Cell Imaging Several alternatively spliced transcript variantsThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.