TFIIH p44 Polyclonal Antibody, 50ul Roller Bottles Favors Hoogsteen base-pairing in the

Favors Hoogsteen base-pairing in the active site

the encoded protein is specifically expressed in the testis

Reduced expression of this gene leads to the premature loss of centromeric cohesion

is associated with a milder form of the disorder called van Buchem disease

TFIIH p44 Polyclonal Antibody, 50ul Roller Bottles Favors Hoogsteen base-pairing in theGTF2H2 is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. GTF2H2 is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the