S10AE Polyclonal Antibody, 20ul Biochemical Reagents Dysregulation of this gene has

Dysregulation of this gene has been associated with the growth and progression of certain cancers

This gene is a candidate for the ovarian tumor suppressor gene

It is primarily an alpha-helical protein with very little coiled coil| and binds directly to the largest subunit (p150) of dynactin

a proteoglycan found in the extracellular matrix and most cells which is involved in cell migration and differentiation

S10AE Polyclonal Antibody, 20ul Biochemical Reagents Dysregulation of this gene hasThis gene encodes a member of the S100 protein family which contains an EF hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828).