HPGDS Polyclonal Antibody, 20ul Mini dry bath Two alternatively spliced transcript variants

Two alternatively spliced transcript variants encoding distinct isoforms have been described

These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures

The filaggrin-like protein encoded by this gene is upregulated by calcium| proteolyzed by calpain 1| and is involved in epithelial homeostasis

but the full-length nature of these variants has not been determined

HPGDS Polyclonal Antibody, 20ul Mini dry bath Two alternatively spliced transcript variantsProstaglandin D synthase is a sigma class glutathione S transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes.