JAK2 mouse Monoclonal Antibody(3F10), 20ul Immune Cell Analysis Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding distinct isoforms have been reported

An important paralog of this gene is SCNN1G

The sestrin 1 mediates p53 inhibition of cell growth by activating AMP-activated protein kinase

The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization

JAK2 mouse Monoclonal Antibody(3F10), 20ul Immune Cell Analysis Alternatively spliced transcript variants encodingThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.