DLC-1 Polyclonal Antibody, 50ul Serum & Sample Tubes Loss or altered expression of

Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers

and pancreas

membrane-associated proteins that recruit effector proteins in the GTP-bound state and inactive cytosolic proteins when in a GDP-bound state

It is specifically expressed in the periderm

DLC-1 Polyclonal Antibody, 50ul Serum & Sample Tubes Loss or altered expression ofDLC1 encodes a GTPase activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to