Mcl-1(Phospho-Ser159/Thr163) Rabbit Polyclonal Antibody, 50ul Immune Cell Preparation This gene's protein is found

This gene's protein is found in the cytoplasm| yet it lacks the nuclear localization signals found in other subfamily members

often at the N- or C-terminus of the protein

and may promote complex formation at DNA repair sites

Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy

Mcl-1(Phospho-Ser159/Thr163) Rabbit Polyclonal Antibody, 50ul Immune Cell Preparation This gene's protein is foundThis gene encodes an anti apoptotic protein which is a member of the Bcl 2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death inducing.