BMP-3A Polyclonal Antibody, 50ul[BT-AP00924] Protein Research Ubiquitously expressed with higher expression

Ubiquitously expressed with higher expression in heart and skeletal muscle

RF1 and RF2

MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment

This protein also plays a role in synapse organization between parallel fibers and Purkinje cells

BMP-3A Polyclonal Antibody, 50ul[BT-AP00924] Protein Research Ubiquitously expressed with higher expressionBMP3 encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. This protein suppresses osteoblast differentiation, and negatively