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JAK2 mouse Monoclonal Antibody(3F10), 50ul Micro Centrifuge Tubes The G protein-coupled receptor kinase

SKU: 20456295451

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JAK2 mouse Monoclonal Antibody(3F10), 50ul Micro Centrifuge Tubes The G protein-coupled receptor kinaseThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

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Description

The G protein-coupled receptor kinase 6 phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation

Members of this family are involved in a variety of cellular processes

are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin

Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of CRHR1

JAK2 mouse Monoclonal Antibody(3F10), 50ul Micro Centrifuge Tubes The G protein-coupled receptor kinaseThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

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