alpha-E-Catenin(Phospho-Ser652) Rabbit Polyclonal Antibody, 50ul Recombinant Ab Production This gene encodes a core

This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle

this protein co-expresses with other family members in the nucleus and in stress fibers

Mutations in this gene are associated with Nijmegen breakage syndrome| an autosomal recessive chromosomal instability syndrome characterized by microcephaly| growth retardation| immunodeficiency| and cancer predisposition

Alternative splicing results in multiple transcript variants encoding distinct protein isoforms

alpha-E-Catenin(Phospho-Ser652) Rabbit Polyclonal Antibody, 50ul Recombinant Ab Production This gene encodes a coreThis gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension resulting in the reconfiguration of cadherin actin filament connections. Certain mutations in