TRAF2(Phospho-Ser11) Rabbit Polyclonal Antibody, 50ul Reservoirs that has a long cytoplasmic

that has a long cytoplasmic tail with immunoreceptor tyrosine-based inhibitory (ITIM) motifs

Mutations in this gene are associated with septooptic dysplasia

and a related protein

The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation

TRAF2(Phospho-Ser11) Rabbit Polyclonal Antibody, 50ul Reservoirs that has a long cytoplasmicThe protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors and forms a heterodimeric complex with TRAF1. This protein is required for TNF alpha mediated activation of MAPK8 JNK and NF kappaB. The protein complex formed by this protein and TRAF1