FAN Rabbit Polyclonal Antibody, 20ul Drying & Desiccation The mu class of enzymes

The mu class of enzymes functions in the detoxification of electrophilic compounds| including carcinogens| therapeutic drugs| environmental toxins and products of oxidative stress| by conjugation with glutathione

while the HLH domain facilitates the mono- and heterodimeric interactions required for efficient DNA binding

The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia

This gene has no introns

FAN Rabbit Polyclonal Antibody, 20ul Drying & Desiccation The mu class of enzymesThis gene encodes a WD repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF mediated activation of neutral sphingomyelinase and may play a role in regulating TNF induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.