SRY Polyclonal Antibody, 20ul[BT-AP08576] Hepatocytes Three alternatively spliced transcripts encoding

Three alternatively spliced transcripts encoding different isoforms have been described for this gene

and has been found to be overexpressed in 10% of clear cell renal carcinomas

Mutations in EPCAM result in congenital tufting enteropathy

ACC-alpha is highly enriched in lipogenic tissues

SRY Polyclonal Antibody, 20ul[BT-AP08576] Hepatocytes Three alternatively spliced transcripts encodingThis intronless gene encodes a transcription factor that is a member of the high mobility group (HMG) box family of DNA binding proteins. Sex determining region Y protein is the testis determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.