JAK2 Rabbit Polyclonal Antibody, 20ul Recombinant Protein Expression Studies of the mouse homolog

Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways

ubcellular location: cell membrane

An important paralog of this gene is NDUFC2-KCTD14

This gene encodes a subunit of the Integrator complex which is involved in the cleavage of small nuclear RNAs U1 and U2 within the nucleus

JAK2 Rabbit Polyclonal Antibody, 20ul Recombinant Protein Expression Studies of the mouse homologThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.