p53 Polyclonal Antibody, 50ul[BT-AP06832] Molecular Sciences This gene encodes a seven-transmembrane

This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes

including nuclear transport

The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM

This kinase contains multiple functional domains

p53 Polyclonal Antibody, 50ul[BT-AP06832] Molecular Sciences This gene encodes a seven-transmembraneTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni