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RyR-2 Polyclonal Antibody, 20ul sgRNA Oligos 1999 [PubMed 10370142])

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RyR-2 Polyclonal Antibody, 20ul sgRNA Oligos 1999 [PubMed 10370142])RYR2 (ryanodine receptor 2) encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in RYR2 are associated with stress induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular

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Description

1999 [PubMed 10370142])

The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids

The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption

It interacts with MDM2 and enhances p53/TP53 ubiquitination

RyR-2 Polyclonal Antibody, 20ul sgRNA Oligos 1999 [PubMed 10370142])RYR2 (ryanodine receptor 2) encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in RYR2 are associated with stress induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular

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