Rat Growth/Differentiation Factor 11, GDF11 ELISA Kit, 96T DNA/RNA Isolation & Purification stimulating IRF5 homodimerization and translocation

stimulating IRF5 homodimerization and translocation into the nucleus (By similarity)

Under conditions of nutrient depletion

This gene encodes a protein with an N-terminal filamin-binding domain| a central proline-rich domain| and| multiple C-terminal LIM domains

Also involved in the integration of the circadian rhythms and energy metabolism

Rat Growth/Differentiation Factor 11, GDF11 ELISA Kit, 96T DNA/RNA Isolation & Purification stimulating IRF5 homodimerization and translocationSecreted signal that acts globally to specify positional identity along the anterior posterior axis during development. May play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. Signals through activin receptors type 2, ACVR2A and ACVR2B, and activin receptors type 1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3.