Porcine Plasminogen Activator Inhibitor 1, PAI-1 ELISA Kit, 96T Filtration GO annotations related to this

GO annotations related to this gene include G-protein coupled receptor activity and complement component C5a binding

This gene originally was thought to be located at 17q21

It was found with a frequency of about 32%

Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P)

Porcine Plasminogen Activator Inhibitor 1, PAI-1 ELISA Kit, 96T Filtration GO annotations related to thisSerine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue type plasminogen activator (PLAT) and urokinase type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease