IRAK-1(Phospho Thr387) Polyclonal Antibody, 100ul Recombinant Protein Expression The protein kinase encoded by

The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis

mutations in this gene are thought to confer a predisposition to sarcomas

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This protein forms a complex with the product of the adjacent recombination activating gene 1

IRAK-1(Phospho Thr387) Polyclonal Antibody, 100ul Recombinant Protein Expression The protein kinase encoded byThis gene encodes the interleukin 1 receptor associated kinase 1, one of two putative serine threonine kinases that become associated with the interleukin 1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1 induced upregulation of the transcription factor NF kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.