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DEN1B Rabbit Polyclonal Antibody, 100ul Stepper The N-terminal extended form is

SKU: 27089985286

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DEN1B Rabbit Polyclonal Antibody, 100ul Stepper The N-terminal extended form isClathrin (see MIM 118955) mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family such as DENND1B function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein 2 (AP2; see MIM 601024). Thus connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson 2010

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Description

The N-terminal extended form is targeted to the mitochondrion

These molecules activate latent RNase L

The protein encoded by this gene mediates calcium entry| and this entry is potentiated by calcium store depletion

The leukocyte associated immunoglobulin like receptor 1 encoded by LAIR1 is an inhibitory receptor found on peripheral mononuclear cells

DEN1B Rabbit Polyclonal Antibody, 100ul Stepper The N-terminal extended form isClathrin (see MIM 118955) mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family such as DENND1B function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein 2 (AP2; see MIM 601024). Thus connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson 2010

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