Vav1(Phospho Tyr174) Polyclonal Antibody, 50ul Funnels Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants differring in the 5' UTR have been described| but the full-length nature of these variants has not been determined

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MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al

Among its related pathways are DNA Double-Strand Break Repair and Fanconi anemia pathway

Vav1(Phospho Tyr174) Polyclonal Antibody, 50ul Funnels Multiple alternatively spliced transcript variantsThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.