IGF-IR Polyclonal Antibody, 50ul[BT-AP04399] Cell Culture Flasks EF-hand calcium binding domain 5)

EF-hand calcium binding domain 5) is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes

but its biological validity has not been determined

Studies in mice suggest that this gene functions in wound healing and abdominal wall development

Contains 11 LRR (leucine-rich) repeats

IGF-IR Polyclonal Antibody, 50ul[BT-AP04399] Cell Culture Flasks EF-hand calcium binding domain 5)IGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms