CD59 Polyclonal Antibody, 100ul[BT-AP01729] Peptide Library Mutations in this gene have

Mutations in this gene have been associated with Krabbe disease| also known as globoid cell leukodystrophy

Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b

It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation| DNA repair| and/or cell cycle checkpoint control

AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation

CD59 Polyclonal Antibody, 100ul[BT-AP01729] Peptide Library Mutations in this gene haveThe Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP 1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.