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GRK 2(Phospho Ser29) Polyclonal Antibody, 20ul 3D Cell Culture Consumables Mutations in this gene may

GRK 2(Phospho Ser29) Polyclonal Antibody, 20ul 3D Cell Culture Consumables Mutations in this gene may

Name: GRK 2(Phospho Ser29) Polyclonal Antibody, 20ul 3D Cell Culture Consumables Mutations in this gene may
Brand: matisco.be
SKU: 29201829130
Price: 111.00 USD
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SKU: 29201829130

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GRK 2(Phospho Ser29) Polyclonal Antibody, 20ul 3D Cell Culture Consumables Mutations in this gene mayThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

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Description

Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases

also acts as a transcriptional repressor

craniofacial anomalies

An important paralog of this gene is CSNK1G2

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