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Rb(Phospho Ser795) Polyclonal Antibody, 100ul Cryogenic Vials May contribute to signal transduction

Rb(Phospho Ser795) Polyclonal Antibody, 100ul Cryogenic Vials May contribute to signal transduction

Name: Rb(Phospho Ser795) Polyclonal Antibody, 100ul Cryogenic Vials May contribute to signal transduction
Brand: matisco.be
SKU: 31380667635
Price: 141.00 USD
Availability: InStock
Rating: 4.1593 (17 reviews)

SKU: 31380667635

4.2

EUR141.00 EUR178.00

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Rb(Phospho Ser795) Polyclonal Antibody, 100ul Cryogenic Vials May contribute to signal transductionThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

May contribute to signal transduction through its intracellular domain

Mutations in CTSA are associated with galactosialidosis

and the counterbalancing phosphatase

|PTM:Monomethylated| dimethylated or trimethylated at Lys-21

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