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TECT3 Rabbit Polyclonal Antibody, 100ul Immunoassays as with the oncogenic PLZF-RAR

SKU: 32211945778

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TECT3 Rabbit Polyclonal Antibody, 100ul Immunoassays as with the oncogenic PLZF-RARThis gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Description

as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias

that associates with a variety of regulatory subunits

This gene is prominently expressed in the kidney

The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain

TECT3 Rabbit Polyclonal Antibody, 100ul Immunoassays as with the oncogenic PLZF-RARThis gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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