Epsin 2 Polyclonal Antibody, 50ul Drying & Desiccation Contains 1 pseudo-CRIB domain

Contains 1 pseudo-CRIB domain

This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila disc large tumor suppressor gene

The protein encoded by CDK17 (cyclin dependent kinase 17) belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases

which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot

Epsin 2 Polyclonal Antibody, 50ul Drying & Desiccation Contains 1 pseudo-CRIB domainEPN2 encodes a protein which interacts with clathrin and adaptor related protein complex 2, alpha 1 subunit. Epsin 2 is found in a brain derived clathrin coated vesicle fraction and localizes to the peri Golgi region and the cell periphery. The protein is thought to be involved in clathrin mediated endocytosis. Alternate splicing of EPN2 results in multiple transcript variants encoding different isoforms