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Tuberin/TSC2(Phospho-Ser664) Rabbit Polyclonal Antibody, 50ul Long RNA Synthesis GAS1 blocks entry to S

SKU: 32822065690

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Tuberin/TSC2(Phospho-Ser664) Rabbit Polyclonal Antibody, 50ul Long RNA Synthesis GAS1 blocks entry to SMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells

The enzyme requires NAD(H) as a coenzyme| and is inhibited by inorganic phosphate

The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin

Osteoporotic bones are more at risk of fracture

Tuberin/TSC2(Phospho-Ser664) Rabbit Polyclonal Antibody, 50ul Long RNA Synthesis GAS1 blocks entry to SMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

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