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Rat Nf-Kappa-B Inhibitor Alpha, NFKBIA ELISA Kit, 96T Reservoirs Isoform 3 may play a

SKU: 32953482093

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Rat Nf-Kappa-B Inhibitor Alpha, NFKBIA ELISA Kit, 96T Reservoirs Isoform 3 may play aInhibits the activity of dimeric NF kappa B REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription (By similarity).

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Description

Isoform 3 may play a role in early spermatogenesis

Interacts directly with BNIP1/SEC20L and ZW10

and functions as a receptor for angiotensin II

E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors

Rat Nf-Kappa-B Inhibitor Alpha, NFKBIA ELISA Kit, 96T Reservoirs Isoform 3 may play aInhibits the activity of dimeric NF kappa B REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription (By similarity).

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