Rtn-3 Monoclonal Antibody, 100ul[BT-MCA1110] Isothermal Amplification Orphan receptor with constitutive G(i)

Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP

Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D

and has two modified domains that are thought to have lost their calcium binding capability

This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence

Rtn-3 Monoclonal Antibody, 100ul[BT-MCA1110] Isothermal Amplification Orphan receptor with constitutive G(i)This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta amyloid converting enzyme 1 (BACE1), and the production of amyloid beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid beta, suggesting that reticulon proteins are negative modulators of BACE1 in