CCRL1 Polyclonal Antibody, 50ul[BT-AP01326] Cellular Function Assays The RUN domain is involved

The RUN domain is involved in Ras-like GTPase signaling| and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif

a calcium binding protein that is the C-propeptide of this collagen molecule

This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts

Mutations in this gene have be associated with autosomal recessive Segawa syndrome

CCRL1 Polyclonal Antibody, 50ul[BT-AP01326] Cellular Function Assays The RUN domain is involvedThe protein encoded by ACKR4 is a member of the G protein coupled receptor family, and is a receptor for C C type chemokines. Atypical chemokine receptor 4 has been shown to bind dendritic cell and T cell activated chemokines including CCL19 ELC, CCL21 SLC, and CCL25 TECK. A pseudogene of ACKR4 is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described.