HEN1/2 Polyclonal Antibody, 50ul Molecular Biology VRK3 (vaccinia related kinase 3)

VRK3 (vaccinia related kinase 3) encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases

Expression of this gene is repressed by phsphorylation

Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site

it is normally found in the nucleus except during mitosis

HEN1/2 Polyclonal Antibody, 50ul Molecular Biology VRK3 (vaccinia related kinase 3)The helix loop helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC, LYL1, E2A, and SCL.