UBP49 Polyclonal Antibody, 100ul ROS/Nitric Oxide Detection In a non-canonical activation pathway|

In a non-canonical activation pathway| the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB| inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes

and at lower levels on dendritic cells and natural killer cells

as well as increased surface expression of cell activation markers

PTM:Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation

UBP49 Polyclonal Antibody, 100ul ROS/Nitric Oxide Detection In a non-canonical activation pathway|Catalytic activity: Ubiquitin C terminal thioester + H(2)O = ubiquitin + a thiol.,Belongs to the peptidase C19 family.,Contains 1 UBP type zinc finger.,